Lumateperone brand name May 25, 2025 · Evidence-based interaction details between Lumateperone (brand name(s): Caplyta) and Anodyne Therapy, including interaction severity and how likely the interaction is to occur. 4%. [1] Hepatic Impairment. Brand names IMPORTANT WARNING: Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as lumateperone have an increased Lumateperone is not approved for the treatment of patients with dementia-related psychosis. Brand Name(s): Caplyta. Compared to other antipsychotic medications, it has a very low incidence of extrapyramidal symptoms and greater efficacy in treating the negative symptoms of schizophrenia. Name Lumateperone tosylate Drug Entry Lumateperone. , Hwang B. Our telemedicine providers are available to support you in managing your treatment effectively. May 25, 2025 · Evidence-based interaction details between Lumateperone (brand name(s): Caplyta) and Kiwi, including interaction severity and how likely the interaction is to occur. Learn about its mechanism of action, price, side effects, warnings, and interactions. Mar 13, 2025 · Lumateperone (Caplyta) is a brand name of an oral capsule used to treat schizophrenia or bipolar depression in adults. Always consult your healthcare provider before starting or changing your dosage. This drug is part of a newer generation of antipsychotics that aims to provide effective treatment with fewer side effects compared to older medications. Adult Medication Brand Names: US. Trademarks, brands, logos, and copyrights are the property of their respective owners. It is also known by its brand name Caplyta. E. Nov 13, 2024 · Common Brand Name(s): Caplyta; Common Generic Name(s): lumateperone, lumateperone tosylate; Pronunciation: kap-LITE-ah, LOO-ma-TE-per-one; Drug Classes: atypical antipsychotic, Generic name: lumateperone (loo-mah-te-per-one) Brand name: Caplyta™. Lumateperone rebalances dopamine, serotonin, and glutamate to improve thinking, mood, and behavior. 1 This medicine is used for the following purposes: bipolar disorder, schizophrenia. There is a higher chance of death in older adults who take this drug for mental problems caused This medicine is used for the following purposes: bipolar disorder, schizophrenia. Last Lumateperone, sold under the brand name Caplyta, is a medication used to treat schizophrenia. Its approval on December 20, 2019, and subsequent expansion for bipolar depression treatment on December 17, 2021, mark significant advancements in the management of these conditions. R. There is limited information regarding Lumateperone tosylate Look-Alike Drug Names in the drug label. 5 mg, 21 mg, 42 mg) Drug class: Atypical antipsychotics. , New York, NY Dosing forms: 42-mg oral capsule (taken with food). 0004 mg/kg, with a relative infant dose (RID) of 0. (loo" ma te' per one) Brand Name(s): Caplyta® Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and This medicine is used for the following purposes: bipolar disorder, schizophrenia. Oral Promising advancements in pharmacological treatments have brought optimism to the field of psychiatry. GoodRx works to make its website accessible to all, including those with disabilities. Look-Alike Drug Names. It is also indicated for depressive episodes associated Lumateperone Tosylate, sold under the brand name Caplyta, is a antipsychotic medication approved for the treatment of schizophrenia as well as bipolar depression. Common side effects include sleepiness and dry mouth. While most individuals tolerate Lumateperone well, it may cause side effects in some cases. It is approved for the treatment of schizophrenia as well as bipolar depression, as either monotherapy or adjunctive therapy with lithium or valproate. The recommended dosage in adults is 42 mg once daily. What Conditions Does Lumateperone Treat? LUMATEPERONE (LOO ma TEP e rone) treats schizophrenia and bipolar depression. Expert Opin Pharmacother, 2019, 1 For bipolar I and bipolar II depression in adults CAPLYTA is a once-daily pill proven to deliver significant symptom relief from bipolar I and bipolar II depression. Lumateperone systemic is used in the treatment of: Bipolar Disorder; Schizophrenia Generic Name Lumateperone DrugBank Accession Number DB06077 Background. Lumateperone is available under the following different brand names: Caplyta Jun 17, 2022 · Lumateperone (US brand name Caplyta®) is a second-generation (“atypical”) antipsychotic that was approved by the FDA in 2019 and became available in the US in 2020. What is Caplyta (Lumateperone)? CAPLYTA is indicated for the treatment of: Schizophrenia in adults May 25, 2025 · Evidence-based interaction details between Lumateperone (brand name(s): Caplyta) and Scopolia, including interaction severity and how likely the interaction is to occur. Jan 28, 2025 · Caplyta is used to treat schizophrenia or depression associated with bipolar disorder. While traditional antipsychotics primarily target dopamine receptors, lumateperone acts as a serotonin receptor modulator and a dopamine receptor phosphoprotein Lumateperone, under the brand name Caplyta, is FDA approved for the treatment of schizophrenia and bipolar depression in adults. On this page, we will provide basic information about this medication. g. CAPLYTA can be taken alone or with lithium or va Fast facts about lumateperone Brand name: Caplyta Class: Oral atypical antipsychotic Indication: Adults with schizophrenia Approval date: December 20, 2019 Availability date: March 31, 2020 Manufacturer: Intra-Cellular Therapies, Inc. On 20 December 2019, the US Food and Drug Administration (FDA) approved lumateperone, marketed under the brand name CAPLYTA ®, for the treatment of schizophrenia in adults, following evidence from three double-blind, placebo-controlled trials (NCT01499563, NCT02282761, NCT02469155) [3,5]. Warning. J. Please see Medication Guide, including Boxed Warnings. Caplyta. 56% of reviewers reported a positive experience, while 28% reported a negative experience. Treatment for: Schizophrenia, Bipolar Disorder. Get ready for your next visit with your healthcare provider with helpful questions to start the conversation about CAPLYTA. Approval: 2019 . Lumateperone reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). Neuropsychopharmacology, 2019, 44(3), 598-605 Pubmed ; Vyas P. Caplyta is indicated for the treatment of: Schizophrenia in adults. Lumateperone (Caplyta) is a second-generation antipsychotic. Vanover K. 5, 10. Jun 5, 2023 · Lumateperone is available as capsules of 10. It is also known as a second generation antipsychotic (SGA) or atypical antipsychotic. , allergic dermatitis, papular rash, and generalized rash), and urticaria. Coadministration of grapefruit or grapefruit juice with lumateperone should be avoided. Mar 13, 2025 · Caplyta (lumateperone) is a brand-name medication doctors may prescribe for schizophrenia and depressive episodes related to bipolar I disorder and bipolar II disorder. Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Products containing lumateperone lumateperone systemic. Form: Capsule. Lumateperone also has moderate binding affinity for dopamine D 1 (41 nM) and D 4 and adrenergic alpha 1A and alpha 1B receptors (K i projected at < 100 nM) but has low binding affinity (less than 50% inhibition at 100 nM) for muscarinic and histaminergic receptors. Lumateperone. com. Reference standards of Lumateperone Tosylate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below. Names of Lumateperone Medication. Manufacturer. Do not take more or less of it or take it more often than prescribed by your doctor. Lumateperone This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. It belongs to a group of medications called antipsychotics. This medicine is used for the following purposes: bipolar disorder, schizophrenia. Brand Names. Bioavailability 4. 6 out of 10 from a total of 190 reviews on Drugs. 5, or 21 mg/kg/day for the first 385 days, then doses were reduced for the two higher dose groups so that the females were administered 3. 5, 7 or 14 mg/kg/day and females were administered lumateperone at oral doses of 3. Lumateperone is an atypical antipsychotic medication sold under the brand name Caplyta. 1 Jun 17, 2024 · One of the main differences between these medications is side effects. Caplyta (lumateperone) is less likely to cause certain side effects, such as movement-related side effects and weight gain, than quetiapine (Seroquel). Common side effects include somnolence, fatigue, nausea, dizziness, dry mouth, nasal congestion, anxiety, restlessness and weight gain. Reactions have included pruritus, rash (e. 5, 21 and 42 mg under the brand name Caplyta. May 25, 2025 · Evidence-based interaction details between Lumateperone (brand name(s): Caplyta) and Theanine, including interaction severity and how likely the interaction is to occur. WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS. Systemic exposure to lumateperone is increased in individuals with hepatic impairment (14, 137, or 80% higher in individuals with Child-Pugh class A, B, or C, respectively) compared with individuals with normal hepatic function Jun 30, 2023 · Lumateperone has moderate binding affinity for serotonin transporters (K i = 33 nM). Schizophrenia is a complex mental illness and impacts approximately 1% of the population. If you are having difficulty accessing this website, please call or email us at 1-855-268-2822 or ada@goodrx. Brand Names: US Caplyta ® Lumateperone 1/12 Brand Name. Experts aren't sure exactly how Caplyta works but suggest it may be by blocking the receptors for certain chemical neurotransmitters in the brain, such as serotonin and dopamine. CAPLYTA® Manufactured by Intra-Cellular Therapies, Inc. Lumateperone is a prescription medication used to treat the symptoms of schizophrenia and bipolar disorder in adults. All FDA warnings are at the end of this fact sheet. Dopamine D2 receptor occupancy of lumateperone (ITI-007): a Positron Emission Tomography Study in patients with schizophrenia. What is lumateperone and what does it treat? Lumateperone is a medication that works in the brain to treat schizophrenia. 5 mg, 21 mg, and 42 mg: Oral tablets: 20 mg, 40 mg, 60 mg, 80 mg, and 120 mg: What is the standard dosage? 42 mg by mouth once daily May 25, 2025 · Evidence-based interaction details between Lumateperone (brand name(s): Caplyta) and Cursed Buttercup, including interaction severity and how likely the interaction is to occur. Symptoms of schizophrenia include: Lumateperone is used to treat certain mental/mood disorders (such as schizophrenia, episodes of depression associated with bipolar disorder). 5, 7 or 14 mg/kg/day Brand name: Caplyta Generic name: lumateperone Dosage form: Capsules Company: Intra-Cellular Therapies, Inc. Lumateperone is used to treat certain mental/mood disorders (such as schizophrenia, episodes of depression associated with bipolar disorder). It works by balancing the levels of dopamine and serotonin in your brain, substances that help regulate mood, behaviors, and thoughts. It is used in the treatment of patients with schizophrenia. 7 Although there are several antipsychotics including aripiprazole, paliperidone and clozapine available for clinical use, they are generally accompanied by significant metabolic and/or neurological adverse effects. Lumateperone may help control your symptoms, but it will not cure your condition. Jul 13, 2023 · In Sprague-Dawley rats, males were administered lumateperone (free base) at oral doses of 3. An evaluation of lumateperone tosylate for the treatment of schizophrenia. Continue to take lumateperone even if you feel well. Please consult them before taking this medication. Medically reviewed by Carmen Pope, BPharm. Generic Name: Lumateperone. Contraindications: CAPLYTA is contraindicated in patients with known hypersensitivity to lumateperone or any components of CAPLYTA. MANAGEMENT: Lumateperone should be administered with food. Brand name: Caplyta Drug class: atypical antipsychotics. 06% the maternal weight-adjusted dosage Mar 15, 2020 · Brand Name(s): Caplyta® IMPORTANT WARNING: Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as lumateperone have an Dec 20, 2019 · Caplyta is a brand name of lumateperone, approved by the FDA in the following formulation(s): CAPLYTA (lumateperone tosylate - capsule;oral) Manufacturer: INTRA-CELLULAR Approval date: December 20, 2019 Strength(s): EQ 42MG BASE ; Manufacturer: INTRA-CELLULAR Approval date: April 22, 2022 Strength(s): EQ 10. Apr 10, 2024 · Mechanism of Action between lumateperone and other antipsychotics Lumateperone, also known by its brand name Caplyta, has a unique mechanism of action compared to other antipsychotics. Drugs used to treat depression can help prevent suicidal thoughts/attempts and provide other important benefits. . Protein binding 97. Caplyta (lumateperone) is an atypical antipsychotic for the treatment of schizophrenia and bipolar depression. It is approved for schizophrenia and bipolar depression, and acts on serotonin, dopamine, and alpha receptors. Lumateperone is an FDA-approved antipsychotic medication. US Brand Name: Caplyta (Lumateperone) CAPLYTA (lumateperone) capsules, for oral use Initial U. Drug Shortage Status Price Jan 7, 2025 · When administered with a high-fat meal, lumateperone Cmax decreased by 33% while its AUC increased by 9% and its median time to peak plasma concentration (Tmax) was delayed by about 1 hour. It is taken by mouth. Generic Name. Oral agent. The generic name is lumateperone. CAPLYTA is Lumateperone is used to treat certain mental/mood disorders (such as schizophrenia, episodes of depression associated with bipolar disorder). If you find the side effects from Caplyta too difficult to tolerate, talk with your doctor or pharmacist. com so that we can provide you with the services you require Nov 5, 2024 · Lumateperone, an atypical antipsychotic, is currently approved under the brand name Caplyta ® for the treatment of schizophrenia in adults. [1] Mar 15, 2020 · Take lumateperone exactly as directed. Lumateperone, sold under the brand name Caplyta, is an atypical antipsychotic medication of the butyrophenone class. May 25, 2025 · Evidence-based interaction details between Lumateperone (brand name(s): Caplyta) and Manaca, including interaction severity and how likely the interaction is to occur. Note: This is equivalent to the Lumateperone, sold under the brand name Caplyta, is an atypical antipsychotic medication of the butyrophenone class. Lumateperone, marketed under the brand name Caplyta (Intra-Cellular Therapies, Inc. Aug 7, 2024 · Brand/generic status: Brand: Brand and generic: What is the generic name? The active ingredient is lumateperone, but there is no generic available. Lurasidone : What form(s) does the drug come in? Oral capsules: 10. It is approved for the treatment of schizophrenia as well as bipolar depression, as either monotherapy or adjunctive therapy (with lithium or valproate). Other side effects may include neuroleptic malignant syndrome, tardive dyskinesia, diabetes, weight gain, low white blood cells, seizures, and poor coordination. S. , Brašić J. May 25, 2025 · Evidence-based interaction details between Lumateperone (brand name(s): Caplyta) and Calabash Chalk, including interaction severity and how likely the interaction is to occur. Lumateperone is a brand name of a medicine used to treat schizophrenia and bipolar depression. It is available as a capsule and should not be used with grapefruit juice or for behavioral problems in dementia. Brand names: Caplyta Lumateperone has an average rating of 6. It may take several weeks or longer before you feel the full benefit of lumateperone. In addition, quetiapine (Seroquel) is available as a generic, but Caplyta (lumateperone) is brand name only. Lumateperone (Ingredient) The information below refers to products available in the United States that contain lumateperone. 4% Lumateperone and its metabolites are present in human breast milk in low amounts; in a clinical lactation study, lumateperone was detected in human milk at an estimated daily infant dose 0. May 11, 2025 · Evidence-based interaction details between Lumateperone (brand name(s): Caplyta) and Tyrosine, including interaction severity and how likely the interaction is to occur. See full prescribing information for complete boxed warning. , New York, NY, United States), is one of the most recent additions to the current arsenal of psychotropic medications . et al. 5MG BASE , EQ 21MG BASE LumateperoneBrand Name(s): Caplyta®IMPORTANT WARNING:Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as lumateperone have an increased chance of death during treatment. Atypical antipsychotic. Generic name: lumateperone Dosage form: oral capsule (10. jqu czaeqn unjqa ukqfho pwx qsewkfa lbdoo pkmg drhfa bdrt
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